- RT @UVMLarnerMed: #uvm #vt Lung Center team ready to roll at @LungNE #lungforce walk in #btv @UVMMedCenter https://t.co/eYoSSexW8w 18 hours ago
- RT @PatrickKwan: Thanks @MayorsCAU for having us to celebrate #LGBTPrideNYC at Gracie Mansion! Great seeing my former #NYCSmokeFree colleag… 18 hours ago
- RT @thebetterindia: Mumbai’s Swasthya Sevika Programme Has Trained over 600 Nursing Assistants Across 38 Batches buff.ly/2tUZuqe ht… 18 hours ago
- RT @NHP_INDIA: Learn how healthy diet can prevent diabetes. To know more, please visit: bit.ly/nhp_mdiabetes #SwasthaBharat #NHPIndia h… 18 hours ago
- RT @kimimehra09: inshorts: RT bsindia: World #tobaccoday : 59% Indians want ban on loose #cigarettes mybs.in/2UVqUC8 https://t.co/l… 18 hours ago
- Agree. Deep sleep is true bliss. twitter.com/AyyTangaLangDr… 18 hours ago
- @Syfokazi @sanchx Every cricket team should choose players based on ability, and not gender. I support men and women playing together. 18 hours ago
- just completed 20 minutes of meditation with @InsightTimer. 2 days ago
- The world needed a scapegoat for the shocking loss we suffered. We forget that the game is greater than the greate… twitter.com/i/web/status/8… 2 days ago
- just completed 20 minutes of meditation with @InsightTimer. 3 days ago
- 6 Ways to Weave Self-Care into Your Workday. Be Mindful. hbr.org/2017/06/6-ways… 3 days ago
- Be Mindful at Work. Feel the Breath. lnkd.in/ekm7wxV 3 days ago
- In the AI Age, “Being Smart” Will Mean Something Completely Different hbr.org/2017/06/in-the… 3 days ago
- In the AI Age, “Being Smart” Will Mean Something Completely Different lnkd.in/eUkH2Ey 3 days ago
- Fairfield High School, Bethany Christian Schools win awards for advanced placement classes newsbreakapp.com/n/07oiYrB4?s=a2 3 days ago
- You are in our prayers. twitter.com/terrysulli/sta… 3 days ago
- U r a voice of reason amid rampant emotions. twitter.com/luvsalimkhan/s… 3 days ago
- just completed 17 minutes 12 seconds of meditation with @InsightTimer. 4 days ago
- Maximize leadership and life using AEI∞ Model. Check out my book - 'Sleep Well, Lead Well' - on #BookBuzzr - bit.ly/2ddE7sk 4 days ago
- RT @RanveerOfficial: Win some, lose some..still the greatest team in the world! ✊🏾🇮🇳Solid throughout a hard-fought tournament...proud of yo… 5 days ago
- 51,835 hits
- accidents alcohol Alertness anchor apnea Bedroom benefits of meditation Buddha CPAP Cricket Depression doctor driving drowsiness drowsy drunk Emotional intelligence exercise fatigue females Fibromyalgia grumpy happiness Happiness at work Health helpful High school ICC impaired insomnia Jesus Jet Lag journalist joy kills leadership life mask Meditation Melatonin menstrual menstruation Mindfulness nap napping news Niagara night shift PMS power nap Public Speaking recent REM sleep reporters short sleeper sleep sleep. doctor Sleep apnea Sleep deprivation Sleep disorder sleepiness sleep tips sleepy Slow-wave sleep stress Stress management teen crash rates Tendulkar tips tired travel women work Work–life balance yoga
Sleep apnea linked to cancer death risk
May 25, 12 9:00 PM
Sleep apnea linked to cancer death risk
25 May 2012
Am J Respir Crit Care Med 2012; Advance online publication
MedWire News: Sleep-disordered breathing (SDB), or sleep apnea, is associated with an increased risk for cancer mortality, study findings show.
“Remarkably, the association was stronger in relative terms than that of SDB with mortality from all causes as well as that previously observed for cardiovascular mortality,” say F Javier Nieto, from the University of Wisconsin School of Medicine and Public Health in Madison, USA, and colleagues.
Data on 1522 participants of the Wisconsin Sleep Cohort were studied. Of these, 222 had mild SDB (apnea-hypopnea index [AHI]=5 to 14.9 apnea and hypopnea events per hour of sleep), 84 had moderate SDB (AHI=15 to 29.9), and 59 had severe SDB (AHI=30 or above or had a continuous positive airway pressure [CPAP] device present during sleep assessment).
Over a 22-year period, there were a total of 112 deaths, of which 50 were attributed to cancer, the most frequent being lung cancer (n=8).
After adjusting for age, gender, body mass index, and smoking, SDB showed a dose-response relationship with cancer mortality.
Patients with mild SDB were 1.1 times more likely to die from cancer than individuals without SDB, while those with moderate and severe SDB were a respective 2.0 and 4.8 times more likely. This relationship persisted when patients treated with CPAP were excluded from analyses.
The researchers note that the risk for cancer mortality also increased in line with hypoxemia index severity. Participants in the top hypoxemia index category (11.2% of the night at less than 90% oxygen saturation) had a more than eight times higher risk for cancer mortality than those in the lower category (0.8% of the night at less than 90% oxygen saturation).
This finding supports previous animal studies showing an association between intermittent hypoxia and accelerated cancer progression, and therefore hints at a mediatory effect of hypoxia on increased tumor tissue angiogenesis and resulting cell proliferation and tumor growth, the researchers explain.
They conclude in the American Journal of Respiratory and Critical Care Medicine that if their findings are validated in further clinical and population-based studies, “diagnosis and treatment of SDB in cancer patients may be indicated to prolong survival in cancer patients.”
MedWire (www.medwire-news.md) is an independent clinical news service provided by Springer Healthcare Limited. © Springer Healthcare Ltd; 2012